In this letter, Dijkstra talks about readability and maintainability in a time where those topics were rarely talked about (1968). This letter was one of the main causes why modern programmers don’t have to trouble themselves with goto statements. Older languages like Java and C# still have a (discouraged) goto statement, because they (mindlessly) copied it from C, which (mindlessly) copied it from Assembly, but more modern languages like Swift and Kotlin don’t even have a goto statement anymore.
In most CPU instruction sets, the only conditional instruction is branch (aka goto).
And after each instruction, the CPU go to the next instruction