Reducing Alzheimer’s Risk by 70%: Columbia Scientists Discover Super Gene
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Researchers at Columbia University have identified a genetic variant that may lower the risk of Alzheimer's disease by as much as 70%, potentially protecting thousands of people across the United States from developing the condition. The discovery of the protective variant, which appears to allow

This study attempts to identify the “protective” genetic factors that can modify or reduce the effect of APOEε4 on Alzheimer’s disease risk and to identify new pathogenic mechanisms, proteins, and pathways that inform development of therapeutic targets and diagnostics.

https://link.springer.com/article/10.1007/s00401-024-02721-1 (open access).