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I like that the sign says “will” kill you, not “could”.
If it said “could”, most people would think “probably not me, though”.
Exactly.
Local anesthetics with vasoconstrictors should be used with care in patients taking methamphetamine because they may result in cardiac dysrhythmias, myocardial infarction, and cerebrovascular accident.
Dang.
For some reason “cerebrovascular accident” sounds so funny to me, it’s like “uh oh, seems like my brainy-veiny did an oopsie-whoopsie”.
We don’t make mistakes, we just have happy accidents
A minor infarction.
An actual funeral
F
U
R
R
Y
We really didn’t need this shitty trend from Reddit here…
Take a look at !ask_ouija@lemmy.ml then, you’ll love it!
uwu
What about aderall and vyvanse?
I had to be put under with local anaesthesia for a septoplasty and they said I couldn’t take Vyvanse. I wasn’t going to anyway, it increases your blood pressure. But still good that they tell you.
I’m happy the other person hasn’t had issues, but my dentist called me to let me know they couldn’t put me under because of my prescription… which is Adderall and Vyvanse.
May have just been the Adderall, maybe it was both, but I don’t like going under anyway and was going to use local anesthesia, regardless.
Adderall and Vyvanse are essentially the same drug. You’re on both?
They are related drugs with similar profiles, but they are not the same drug. Vyvanse is Lisdexamfetamine, which is a pro-drug, that your body converts into dextroamphetamine. This can have a big impact on some people, either making the drugs more or less tolerable. Actual metabolic rates for drugs can be significantly different from person to person.
Yes, but Adderall is dextroamphetamine, the drug Vyvanse turns into.
I’m familiar with the pharmacology and their respective mechanisms, just stating that they’re essentially the same drug
They are not the same drug, reread what I said. You can’t be very familiar with pharmacology if you don’t understand prodrugs. They turn into almost Adderall, which isn’t straight dextroamphetamine. This changes how they effect the body, you can say “essentially the same” all you want, but it’s not true when it comes to how they actually impact people. Differing metabolic rates due to naturally different levels of metabolizing enzymes causes prodrugs to have more variance in their peak blood serum levels, it causes later onset of effect and can cause large variance in duration of effect. This can be very helpful or even dangerous for some people. They are not perfectly interchangeable, even if most people find them pretty similar.
Yup. Adderall alone was too much, Vyvanse alone was too little. A max dosage of one and a smidge if the other during the middle of the day if needed?
Just right.
Edit: to go with what the other person said - my metabolism is really fast and I typically run “hot.”
Good thing I only use Ice
Kill You with a capital “K”
I wonder about other amphetamines. Because there’s some things you can take turn into amphetamines when your body processes them, IIRC. There are also medications that are in the same family. I suspect that while people do usually tell their dentist what medications they’re taking when prompted, some people are kind of flaky and forget, while other people might have a reason in their head not to. But, not everybody thinks to disclose stuff like “supplements” which are unregulated, variably legal, and could also pose a health risk if they qualify for this particular scenario. Good of them to tell people that though. I never knew that and I’ve gotten lots of dental work done, although, I’ve never done hard drugs.
I know this isn’t what you meant, but I choose to read this as you calling meth a “supplement”
Hell, they still prescribe meth in some instances. It’s called Desoxyn. Adderall, a drug so commonly used right now there’s a shortage (or was, very recently), is a strong amphetamine. They’re used for a quite a lot medically, and all have similar effects on the body by definition.
The issue at play here is amphetamines are doing a number on vasoconstriction and heart contractility, which then boosts heart rate and BP. This increases the chance of all that fun stuff like ischemic/hemorrhagic stroke, heart attack, or a dangerous dysrhythmia. When you add in anesthesia that has similar effects (vasoconstriction), you massively increase the odds of a complication. Thats without considering the already existing damage likely present in those abusing drugs of this sort.
I always mention vitamins and stuff, just in case. No matter what, I will not lie to my doctor in any situation, it’s one of my rules of life
